Rigidity Analysis Identifies Common Features of Allostery
نویسندگان
چکیده
منابع مشابه
Predicting protein hinge motions and allostery using rigidity theory
Understanding how a 3-D structure of a protein functions depends on predicting which regions are rigid, and which are flexible. One recent approach models molecules as a structure of fixed units (atoms with their bond angles as rigid units, bonds as hinges) plus biochemical constraints coming from the local geometry [6, 13]. This generates a ’molecular graph’ in the theory of combinatorial rigi...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2011
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.12.2247